Use of pressure muscle index to guide pressure support ventilation setting: a study protocol and statistical plan for a prospective randomised controlled proof-of-concept trial.

ABSTRACT:

Introduction

Although pressure support ventilation is one of the most commonly used assisted ventilation modes in intensive care units, there is still a lack of precise strategies for setting pressure support. By performing an end-inspiratory airway occlusion, the difference between the peak and plateau airway pressure, which is defined as pressure muscle index (PMI), can be easily measured on the ventilator screen. Previous studies have shown that PMI is accurate in detecting high and low inspiratory effort. No study has been conducted to investigate the use of PMI as an indicator for setting inspiratory pressure support.

Method and analysis

This is a study protocol for a prospective, single-centre, randomised controlled, pilot trial. Sixty participants undergoing pressure

SUBMITTER: Gao R 

PROVIDER: S-EPMC11298740 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature