Effects of diethylene glycol contamination of pharmaceutical products on unexplained acute kidney injury in children: a systematic review.

ABSTRACT: Unexplained acute kidney injury (AKI) in children owing to diethylene glycol (DEG) contamination during drug production has gained attention in recent years. This qualitative study investigated the effects of DEG exposure on the incidence of unknown AKI in children. A systematic review following the PRISMA (Preferred Reporting Items for Systematic Review and Meta-Analysis) guidelines was proposed to search for studies using predefined search terms in the PubMed, EBSCO, and Web of Science data-bases without publication date restrictions. The inclusion criteria are observational study, case study, case report, and case series design; and having provided accurate data for DEG poisoning and AKI diagnosis in children. All authors performed the study screening, data extraction, and data synthesi

SUBMITTER: Soleman SR 

PROVIDER: S-EPMC11298774 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature