Toward acid- and heparin-free dialysis: the regional anticoagulation approach.

ABSTRACT:

Background

In chronic intermittent hemodialysis, heparin is the standard anticoagulant as is the use of acid-containing dialysate. Regional anticoagulation (RA) with a calcium-free, citrate-containing dialysate has been developed. We compared RA using a calcium-free, citrate-free dialysate, routinely used in our center, versus systemic heparinization.

Methods

In a retrospective, observational, single-center, crossover study, we examined 15 patients undergoing chronic hemodialysis who were at high risk of bleeding and temporarily unable to use heparin. These patients received temporary treatment with RA involving calcium-free and citrate-free dialysate. We compared the dialysis session success rates during two distinct periods: standard heparinization and RA procedure with a

SUBMITTER: Lefevre F 

PROVIDER: S-EPMC11299105 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature