Physiological effects and safety of bed verticalization in patients with acute respiratory distress syndrome.

ABSTRACT:

Background

Trunk inclination in patients with Acute Respiratory Distress Syndrome (ARDS) in the supine position has gained scientific interest due to its effects on respiratory physiology, including mechanics, oxygenation, ventilation distribution, and efficiency. Changing from flat supine to semi-recumbent increases driving pressure due to decreased respiratory system compliance. Positional adjustments also deteriorate ventilatory efficiency for CO₂ removal, particularly in COVID-19-associated ARDS (C-ARDS), indicating likely lung parenchyma overdistension. Tilting the trunk reduces chest wall compliance and, to a lesser extent, lung compliance and transpulmonary driving pressure, with significant hemodynamic and gas exchange implications.

Methods

A prospective,

SUBMITTER: Bouchant L 

PROVIDER: S-EPMC11299299 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature