The profile of oral microbiome in Chinese elderly population associated with aging and systemic health status.

ABSTRACT:

Objective

The health of oral cavity is considered as an important indicator of aging. Oral microbiota is highly associated with the oral health, while the variation of oral microbiome in elderly population and characteristic microbes associated with aging remain unclear.

Subjects and methods

In this study, 130 elderly subjects were recruited and divided into 3 groups according to their age: Stage I group (65 ≤ years < 70), Stage II group (70 ≤ years < 75), and Stage III group (75 ≤ years < 80). Their physiological indices were analyzed with using Illumina MiSeq platform and the oral microbiome was determined by high-throughput sequencing.

Results

Along with aging, the level of fasting blood glucose, systolic pressure and monocytes are significantly increased. No signi

SUBMITTER: Guo L 

PROVIDER: S-EPMC11299356 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature