Body composition and chemotherapy toxicity among women treated for breast cancer: a systematic review.

ABSTRACT:

Purpose

Toxicity is a significant problem among women receiving systemic chemotherapy for breast cancer, with up to 60% experiencing hematologic and 14% experiencing non-hematologic toxicity. Chemotherapy is dosed using body surface area, which does not account for heterogeneity in lean body mass (LBM) and adipose tissue (AT). This systematic review, registered with the PROSPERO International Prospective Register of Systematic Reviews (#CRD42021279874), evaluates associations between body composition and chemotherapy-related toxicity during breast cancer treatment.

Methods

Scientific literature databases (PubMed, Scopus, CINAHL, and CENTRAL) were systematically searched in November 2021 for studies evaluating associations between body composition (assessed using computed tom

SUBMITTER: Wopat H 

PROVIDER: S-EPMC11299853 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature