A stacking ensemble model for predicting the occurrence of carotid atherosclerosis.

ABSTRACT:

Background

Carotid atherosclerosis (CAS) is a significant risk factor for cardio-cerebrovascular events. The objective of this study is to employ stacking ensemble machine learning techniques to enhance the prediction of CAS occurrence, incorporating a wide range of predictors, including endocrine-related markers.

Methods

Based on data from a routine health check-up cohort, five individual prediction models for CAS were established based on logistic regression (LR), random forest (RF), support vector machine (SVM), extreme gradient boosting (XGBoost) and gradient boosting decision tree (GBDT) methods. Then, a stacking ensemble algorithm was used to integrate the base models to improve the prediction ability and address overfitting problems. Finally, the SHAP value method was

SUBMITTER: Zhang X 

PROVIDER: S-EPMC11300245 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature