Understanding Barriers to Guideline-Concordant Treatment in Foregut Cancer: From Data to Solutions.

ABSTRACT:

Background

A large proportion of patients with foregut cancers do not receive guideline-concordant treatment (GCT). This study sought to understand underlying barriers to GCT through a root cause analysis approach.

Methods

A single-institution retrospective review of 498 patients with foregut (gastric, pancreatic, and hepatobiliary) adenocarcinoma from 2018 to 2022 was performed. Guideline-concordant treatment was defined based on National Comprehensive Cancer Network guidelines. The Ishikawa cause and effect model was used to establish main contributing factors to non-GCT.

Results

Overall, 34% did not receive GCT. Root causes of non-GCT included Patient, Physician, Institutional Environment and Broader System-related factors. In decreasing order of frequency, the fol

SUBMITTER: Fonseca AL 

PROVIDER: S-EPMC11300473 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature