Risk Factors for Recurrence After Surgery for Rectal Cancer in a Modern, Nationwide Population-Based Cohort.

ABSTRACT:

Background

The success of modern multimodal treatment in rectal cancer is dependent on risk prediction. Better knowledge of the risk of locoregional and distant recurrence, in relation to preoperative treatment, pathological stage, and commonly used risk factors, is needed when deciding on adjuvant therapy and surveillance.

Methods

The Swedish ColoRectal Cancer Registry was used to identify patients diagnosed with rectal adenocarcinoma between 2011 and 2018. Readily available variables, including patient, tumor, and treatment factors were exposures. Cox proportional hazard models were used to identify important risk factors for recurrence and calculate recurrence risks.

Results

A total of 9428 curatively resected patients were included and followed for a median of 72

SUBMITTER: Doroudian S 

PROVIDER: S-EPMC11300512 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature