Standard versus individualised positive end-expiratory pressure (PEEP) compared by electrical impedance tomography in neurocritical care: a pilot prospective single centre study.

ABSTRACT:

Background

Individualised bedside adjustment of mechanical ventilation is a standard strategy in acute coma neurocritical care patients. This involves customising positive end-expiratory pressure (PEEP), which could improve ventilation homogeneity and arterial oxygenation. This study aimed to determine whether PEEP titrated by electrical impedance tomography (EIT) results in different lung ventilation homogeneity when compared to standard PEEP of 5 cmH₂O in mechanically ventilated patients with healthy lungs.

Methods

In this prospective single-centre study, we evaluated 55 acute adult neurocritical care patients starting controlled ventilation with PEEPs close to 5 cmH₂O. Next, the optimal PEEP was identified by EIT-guided decremental PEEP titration, pr

SUBMITTER: Spatenkova V 

PROVIDER: S-EPMC11300775 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature