Delta-alpha/beta coupling as a signature of visual working memory in the prefrontal cortex.

ABSTRACT: Executive functions, particularly visual working memory, depend on the prefrontal cortex (PFC). Phase-amplitude coupling (PAC) has been proposed as a measure of synchronized brain oscillations. To study the neural correlates of working memory in cross-frequency interactions, local field potential (LFP) recordings were made in the PFC of two macaque monkeys. PAC analysis revealed that the delta band (1-5 Hz) phase modulated the alpha-beta band (8-33 Hz) amplitude throughout task epochs, in both the pre- and post-training stages. The elevation of δ-αβ PAC in the fixation period during post-training was a signature of task learning. Interestingly, the δ-αβ PAC was not enhanced in error trials compared to correct trials, and the subject's performance was strictly dependent on the orchestration

SUBMITTER: Aliramezani M 

PROVIDER: S-EPMC11300902 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature