A nested reciprocal experimental design to map the genetic architecture of transgenerational phenotypic plasticity.

ABSTRACT: Extensive studies have revealed the ecological and evolutionary significance of phenotypic plasticity, but little is known about how it is inherited between generations and the genetic architecture of its transgenerational inheritance. To address these issues, we design a mapping study by growing Arabidopsis thaliana RILs in high- and low-light environments and further growing their offspring RILs from each maternal light environment in the same contrasting environments. This tree-like design of the controlled ecological experiment provides a framework for analysing the genetic regulation of phenotypic plasticity and its non-genetic inheritance. We implement the computational approach of functional mapping to identify specific QTLs for transgenerational phenotypic plasticity. By est

SUBMITTER: Che J 

PROVIDER: S-EPMC11301319 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature