Comparison of adverse events following the second/third dose of BNT162b2 in a medical institute in Japan.

ABSTRACT:

Background

Vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are crucial for ending the pandemic of coronavirus disease 2019 (COVID-19). Currently, the cumulative effect of booster shots of mRNA vaccines on adverse events is not sufficiently characterized.

Methods

A survey-based study on vaccine adverse events was conducted in a Japanese medical institute after the third dose of Pfizer BNT162b2. Adverse events were grouped using network analysis, and a heteroscedastic probit model was built to analyse adverse events.

Results

There were two main clusters of adverse events, systemic and local injection site-associated events. Subject background and the experience of previous vaccine-related adverse events were variably associated with the occ

SUBMITTER: Namiki T 

PROVIDER: S-EPMC11301373 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature