Management and outcomes for older women with early breast cancer treated with primary endocrine therapy (PET).

ABSTRACT:

Background

This study reports the detailed management and outcomes of women treated with Primary Endocrine Therapy (PET) in a large prospective UK cohort of older women (≥70) with breast cancer.

Methods

This was an unplanned secondary analysis of a prospective, multicentre, observational study (The Age Gap study). Data were collected at baseline and regular intervals on patient, tumour and treatment characteristics with tumour RECIST response category recorded. Direct study follow-up was 24 months with longer-term survival data obtained from the UK cancer registry.

Results

The Age Gap study recruited 3316 women across 56 breast units. Primary endocrine therapy (PET) was initiated for 505/3316 (15 %) women; median age was 84 (IQR 79-88) with median follow-up 41.9 month

SUBMITTER: Hubbard T 

PROVIDER: S-EPMC11301393 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature