MRI and Clinical Variables for Prediction of Outcomes After Pediatric Severe Traumatic Brain Injury.

ABSTRACT:

Importance

Traumatic brain injury (TBI) is a leading cause of death and disability in children, and predicting functional outcome after TBI is challenging. Magnetic resonance imaging (MRI) is frequently conducted after severe TBI; however, the predictive value of MRI remains uncertain.

Objectives

To identify early MRI measures that predict long-term outcome after severe TBI in children and to assess the added predictive value of MRI measures over well-validated clinical predictors.

Design, setting, and participants

This preplanned prognostic study used data from the Approaches and Decisions in Acute Pediatric TBI (ADAPT) prospective observational comparative effectiveness study. The ADAPT study enrolled 1000 consecutive children (aged <18 years) with severe TBI betwee

SUBMITTER: Ferrazzano PA 

PROVIDER: S-EPMC11301548 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature