Trends and Age-Period-Cohort Effect on Acute Hepatitis B Incidence - China, 2005-2021.

ABSTRACT:

Introduction

This study analyzed long-term trends in the incidence of acute hepatitis B (AHB) in China, focusing on age, period, and cohort effects on incidence.

Methods

Data on AHB from 2005 to 2021 were extracted from the National Notifiable Disease Reporting System (NNDRS) of China for analysis. Incidences of AHB were calculated by gender and age group using population denominators from the 2000, 2010, and 2020 censuses. Joinpoint regression was employed to evaluate trends, and an age-period-cohort model was used to assess the age, period, and cohort effects.

Results

The annual average incidence of reported AHB in children aged 14 years and below in low, intermediate, and high endemic areas decreased from 1.65, 2.33, and 2.56 per 100,000 in 2005-2010 to 0.56, 0.58,

SUBMITTER: Wang L 

PROVIDER: S-EPMC11301606 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature