Venomics and Peptidomics of Palearctic Vipers: A Clade-Wide Analysis of Seven Taxa of the Genera <i>Vipera</i>, <i>Montivipera</i>, <i>Macrovipera</i>, and <i>Daboia</i> across Turkiye.

ABSTRACT: Snake venom variations are a crucial factor to understand the consequences of snakebite envenoming worldwide, and therefore it is important to know about toxin composition alterations between taxa. Palearctic vipers of the genera Vipera, Montivipera, Macrovipera, and Daboia have high medical impacts across the Old World. One hotspot for their occurrence and diversity is Türkiye, located on the border between continents, but many of their venoms remain still understudied. Here, we present the venom compositions of seven Turkish viper taxa. By complementary mass spectrometry-based bottom-up and top-down workflows, the venom profiles were investigated on proteomics and peptidomics level. This study includes the first venom descriptions of Vipera berus barani

SUBMITTER: Damm M 

PROVIDER: S-EPMC11301686 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature