Neighborhood-level deprivation and survival in lung cancer.

ABSTRACT:

Background

Despite recent advances in lung cancer therapeutics and improving overall survival, disparities persist among socially disadvantaged populations. This study aims to determine the effects of neighborhood deprivation indices (NDI) on lung cancer mortality. This is a multicenter retrospective cohort study assessing the relationship between NDI and overall survival adjusted for age, disease stage, and DNA methylation among biopsy-proven lung cancer patients. State-specific NDI for each year of sample collection were computed at the U.S. census tract level and dichotomized into low- and high-deprivation.

Results

A total of 173 non small lung cancer patients were included, with n = 85 (49%) and n = 88 (51%) in the low and high-deprivation groups, respectively. NDI was s

SUBMITTER: Kennedy K 

PROVIDER: S-EPMC11301857 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature