Real-world diagnostic potential of bacterial biomarkers of canine periodontitis.

ABSTRACT:

Introduction

The objective of this study was to investigate the diagnostic potential of bacterial biomarkers by comparing the performance of molecular detection assays with clinical assessments of dog's oral health performed by veterinarians.

Methods

Supragingival and subgingival plaque samples were collected from 127 client-owned dogs, pre-booked for procedures under general anesthesia, visiting veterinary practices in the United States. DNA was extracted and bacterial biomarkers quantified using quantitative polymerase chain reaction. Gingivitis and periodontitis were recorded by a trained clinician using the Weighted Gingivitis Periodontitis Score which involved assessing the buccal surfaces of 18 teeth while under general anesthesia. Intraoral dental radiographs of the l

SUBMITTER: Wallis CV 

PROVIDER: S-EPMC11301947 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature