Comparative genomic analysis of an emerging Pseudomonadaceae member, Thiopseudomonas alkaliphila.

ABSTRACT: Thiopseudomonas alkaliphila, an organism recently classified within the Pseudomonadaceae family, has been detected in diverse sources such as human tissues, animal guts, industrial fermenters, and decomposition environments, suggesting a diverse ecological role. However, a large knowledge gap exists in how T. alkaliphila functions. In this comparative genomic analysis, adaptations indicative of habitat specificity among strains and genomic similarity to known opportunistic pathogens are revealed. Genomic investigation reveals a core metabolic utilization of multiple oxidative and non-oxidative catabolic pathways, suggesting adaptability to varied environments and carbon sources. The genomic repertoire of T. alkaliphila includes secondary metabolites, such as antimicrob

SUBMITTER: Burcham ZM 

PROVIDER: S-EPMC11302033 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature