Upper respiratory <i>Streptococcus pneumoniae</i> colonization among working-age adults with prevalent exposure to overcrowding.

ABSTRACT: Most pneumococcal disease occurs among infants and older adults and is thought to be driven by the transmission of Streptococcus pneumoniae from young children to these vulnerable age groups. However, pneumococcal disease outbreaks also affect non-elderly adults living or working in congregate, close-contact settings. Little is known about pneumococcal carriage in such populations. From July to November 2020, we collected saliva from low-income adult farmworkers in Monterey County, California, and tested for pneumococcal carriage following culture enrichment via quantitative PCR assays targeting the pneumococcal lytA and piaB genes. Participants were considered to carry pneumococci if lytA and piaB cycle threshold values were both below 40. Among 1,283 pa

SUBMITTER: Parker AM 

PROVIDER: S-EPMC11302326 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature