Experiencing anesthesia and surgery early in life impairs cognitive and behavioral development.

ABSTRACT:

Background

The impact of anesthesia and surgery on neurocognitive and behavioral development in infants and children remains inadequately understood.

Objective

To investigate the impact of early-life exposure to general anesthesia and surgery on cognitive and behavioral development.

Methods and materials

Children aged 0-3 years who underwent general anesthesia and surgical procedures between 2012 and 2015 were included. The cognitive and behavioral development of these children at ages 4-6 years was assessed. Age-, race-, and gender-matched children from the same geographic region, who did not undergo general anesthesia or surgery, served as the control group. The Wechsler Preschool Primary Scale of Intelligence, Fourth Edition (WPPSI-IV) was used to evaluate children

SUBMITTER: Jia X 

PROVIDER: S-EPMC11303152 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature