The network is more important than the node: stereo-EEG evidence of neurocognitive networks in epilepsy.

ABSTRACT:

Introduction

Neuropsychological assessment forms an integral part of the presurgical evaluation for patients with medically refractory focal epilepsy. Our understanding of cognitive impairment in epilepsy is based on seminal lesional studies that have demonstrated important structure-function relationships within the brain. However, a growing body of literature demonstrating heterogeneity in the cognitive profiles of patients with focal epilepsy (e.g., temporal lobe epilepsy; TLE) has led researchers to speculate that cognition may be impacted by regions outside the seizure onset zone, such as those involved in the interictal or "irritative" network.

Methods

Neuropsychological data from 48 patients who underwent stereoelectroencephalography (SEEG) monitoring between 2012 and

SUBMITTER: Murray NWG 

PROVIDER: S-EPMC11303167 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature