A systematic review and meta-analysis of cortisol levels in Plasmodium infections.

ABSTRACT: Malaria has complex interactions with host physiology, including alterations in cortisol levels. Cortisol, a key hormone in the stress response, is known to be dysregulated in various infectious diseases. This systematic review and meta-analysis aimed to elucidate the relationship between Plasmodium infection and cortisol levels, shedding light on the intricate interplay between the parasite and the host's endocrine system. The methodological protocol for assessing cortisol levels in malaria patients was registered in PROSPERO (CRD42024496578), a widely recognized international prospective register of systematic reviews. This registration ensures transparency and minimizes the risk of bias in our research. A comprehensive search strategy was employed across major databases, including Embas

SUBMITTER: Kotepui KU 

PROVIDER: S-EPMC11303744 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature