Incidence and prevalence of primary biliary cholangitis in the Netherlands - A nationwide cohort study.

ABSTRACT:

Background & aims

Although primary biliary cholangitis (PBC) is considered a rare disorder, accurate determination of its incidence and prevalence remains challenging due to limited comprehensive population-based registries. We aimed to assess the incidence and prevalence of PBC in the Netherlands over time through the nationwide Dutch PBC Cohort Study (DPCS).

Methods

DPCS retrospectively included every identifiable patient with PBC in the Netherlands from 1990 onwards in all 71 Dutch hospitals. Incidence and prevalence were assessed between 2008-2018 by Poisson regression between sex and age groups over time.

Results

On the 1^st of January 2008, there were 1,458 patients with PBC in the Netherlands. Between 2008-2018, 2,187 individuals were newly diagnosed,

SUBMITTER: de Veer RC 

PROVIDER: S-EPMC11304051 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature