Association between thymus density loss and efficacy in non-small cell lung cancer patients treated with immune checkpoint inhibitors.

ABSTRACT:

Background

Although the thymus undergoes degeneration with the advancement of age, recent studies have continuously revealed that the thymus possesses the potential for regeneration and may reverse this aging trend. Furthermore, an increasing number of studies indicate an association between thymus function and immunotherapy. Considering that lung cancer patients typically undergo chest computed tomography (CT) scans during treatment, this provides convenient conditions for us to observe thymic remodeling through imaging data. Therefore, exploring the changes in the thymus on CT images is of great significance for understanding its relationship with the efficacy of immunotherapy in non-small cell lung cancer (NSCLC) patients. This study investigated the CT imaging characteristics o

SUBMITTER: Li Y 

PROVIDER: S-EPMC11304139 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature