Lymph node dissection of station 8 improves the survival of T_{≤3 cm}N0M0 lung adenocarcinoma patients.

ABSTRACT:

Background

Mediastinal station 8 lymph node dissection (8LND) is recommended by guidelines but not routinely performed in real world clinical practice. This study aimed to investigate the effect of 8LND on the prognosis of pT_{≤3 cm}N0M0 lung adenocarcinoma.

Methods

Patients undergoing lobectomy were retrospectively enrolled from West China Hospital from 2011 to 2019. Kaplan-Meier method and log-rank test were used to investigate the effects of 8LND on the progression-free survival (PFS), overall survival (OS), and cancer-specific survival (CSS). Propensity score matching (PSM) was used to reduce the confounding effects. Multivariable analysis was conducted to evaluate the effect of 8LND in the matched patients. Subgroup analyses were conducted to further identify pa

SUBMITTER: Wang T 

PROVIDER: S-EPMC11304141 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature