PD-L1 expression in non-small cell lung carcinoma in Latin America: a systematic review and meta-analysis.

ABSTRACT:

Background

Programmed cell death ligand 1 (PD-L1) expression in non-small cell lung carcinoma (NSCLC) is a crucial factor in predicting responses to immunotherapy. This systematic review and meta-analysis focuses on the prevalence of PD-L1 expression and clinicopathological features among Hispanic/Latino (H/L) populations.

Methods

Embase, LILACS, Medline, and Virtual Health Library were searched for studies that evaluated the prevalence of PD-L1 in H/L patients. The protocol was submitted to PROSPERO with ID CRD42023488547. We employed the Joanna Briggs Institute Checklist for Systematic Reviews and Research Syntheses to assess the methodological quality and applicability of the included studies. Meta-analyses were done to determine the prevalence using a random effects mode

SUBMITTER: Parra-Medina R 

PROVIDER: S-EPMC11304153 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature