Tumor cavitation in patients with non-small-cell lung cancer receiving anti-angiogenic therapy with apatinib.

ABSTRACT:

Background

Cavities have been reported in approximately 20% of lung cancer after anti-angiogenesis treatments. However, the effect of which on treatment outcomes remains unclear. This study sought to investigate the incidence and radiographic patterns of tumor cavitation in patients with non-small cell lung cancer (NSCLC) treated with apatinib, and its associations with patients' clinical characteristics and outcomes.

Methods

A total of 300 patients with NSCLC treated with apatinib were retrospectively identified. Baseline and follow-up chest computed tomography scans were reviewed to identify tumor cavitation, and the subsequent filling-in of the cavitation. A multivariate logistic regression analysis was conducted to identify the factors associated with tumor cavitation. S

SUBMITTER: Cai Q 

PROVIDER: S-EPMC11304154 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature