Decompression alone or with fusion for degenerative lumbar spondylolisthesis (Nordsten-DS): five year follow-up of a randomised, multicentre, non-inferiority trial.

ABSTRACT:

Objective

To assess whether decompression alone is non-inferior to decompression with instrumented fusion five years after primary surgery in patients with degenerative lumbar spondylolisthesis.

Design

Five year follow-up of a randomised, multicentre, non-inferiority trial (Nordsten-DS).

Setting

16 public orthopaedic and neurosurgical clinics in Norway.

Participants

Patients aged 18-80 years with symptomatic lumbar spinal stenosis and a spondylolisthesis of 3 mm or more at the stenotic level.

Interventions

Decompression surgery alone and decompression with additional instrumented fusion (1:1).

Main outcome measures

The primary outcome was a 30% or more reduction in Oswestry disability index from baseline to five year follow-up. The predefined non-

SUBMITTER: Kgomotso EL 

PROVIDER: S-EPMC11304163 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature