Identification and analysis of key genes related to efferocytosis in colorectal cancer.

ABSTRACT: The impact of efferocytosis-related genes (ERGs) on the diagnosis of colorectal cancer (CRC) remains unclear. In this study, efferocytosis-associated biomarkers for the diagnosis of CRC were identified by integrating data from transcriptome sequencing and public databases. Finally, the expression of biomarkers was validated by real-time quantitative polymerase chain reaction (RT-qPCR). Our study may provide a reference for CRC diagnosis.

Background

It has been shown that some efferocytosis related genes (ERGs) are associated with the development of cancer. However, it is still uncertain how ERGs may influence the diagnosis of colorectal cancer (CRC).

Methods

In our study, the CRC cohorts were gained from transcriptome sequencing and the gene expression omnibus (GEO) database

SUBMITTER: Zhang S 

PROVIDER: S-EPMC11304617 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature