Associations of bisphenol and phthalate exposure and anti-Mullerian hormone levels in women of reproductive age.

ABSTRACT:

Background

In women, exposure to endocrine disrupting chemicals might accelerate the depletion of the ovarian reserve and might be associated with accelerative reproductive aging and fertility. We examined the longitudinal associations of exposure to bisphenols and phthalates with anti-Müllerian hormone concentrations.

Methods

Pregnant women of 18 years or older that resided in Rotterdam between 2002 and 2006 were eligible for participation in this longitudinal prospective cohort study. We measured urinary bisphenol and phthalate concentration at three time-points in pregnancy among 1405 women, of whom 1322 women had serum Anti-Müllerian Hormone (AMH) measurements 6 and/or 9 years postpartum. We performed linear regression models to assess the association of urinary bispheno

SUBMITTER: Blaauwendraad SM 

PROVIDER: S-EPMC11304696 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature