Impact of neonatal sepsis on neurocognitive outcomes: a systematic review and meta-analysis.

ABSTRACT:

Introduction

Sepsis is associated with neurocognitive impairment among preterm neonates but less is known about term neonates with sepsis. This systematic review and meta-analysis aims to provide an update of neurocognitive outcomes including cognitive delay, visual impairment, auditory impairment, and cerebral palsy, among neonates with sepsis.

Methods

We performed a systematic review of PubMed, Embase, CENTRAL and Web of Science for eligible studies published between January 2011 and March 2023. We included case-control, cohort studies and cross-sectional studies. Case reports and articles not in English language were excluded. Using the adjusted estimates, we performed random effects model meta-analysis to evaluate the risk of developing neurocognitive impairment among ne

SUBMITTER: Ong WJ 

PROVIDER: S-EPMC11304789 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature