Bacteriophages Mediating Effective Elimination of Multidrug-Resistant Avian Pathogenic <i>Escherichia coli</i>.

ABSTRACT:

Background

Avian pathogenic Escherichia coli (APEC) causes colibacillosis and septicemia; in certain cases, mortality leads to economic losses and elicits potential foodborne zoonotic risk. The study aimed to determine the prevalence of APEC pathotypes and serotypes in poultry, followed by characterization for virulence markers and antibiotic sensitivity and analysis of lytic efficacy of bacteriophages in the eradication of APEC.

Methods

We successfully isolated and characterized 34 E. coli isolates from poultry farms. The lytic efficacy of seven bacteriophages, as well as a phage cocktail, was evaluated for biological control of multiple drug resistance (MDR) APEC.

Results

A total of 67.65% of isolated E. coli were APEC. A total of 94.11% of the

SUBMITTER: Koratkar S 

PROVIDER: S-EPMC11304798 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature