Two Novel Bacteriophage Species Against Hybrid Intestinal Pathogenic <i>Escherichia coli</i>/Extraintestinal Pathogenic <i>Escherichia coli</i> Strains.

ABSTRACT:

Background

Colibacillosis caused by Escherichia coli is one of the main problems in the swine industry. In addition, the emergence of antimicrobial resistance and the combination of virulence genes among pathotypes have led to the emergence of more virulent pathogenic E. coli strains. Phage therapy has become a promising approach to address these issues.

Materials and methods

Virulence genes for intestinal pathogenic E. coli (IPEC) and extraintestinal pathogenic E. coli (ExPEC) were investigated in pathogenic E. coli isolated from pigs. In addition, two potential phages, vB_EcoM-RPN187 and vB_EcoM-RPN226, isolated in our previous study, were further characterized in this study.

Results

Both phages were lytic and were highly effective

SUBMITTER: Imklin N 

PROVIDER: S-EPMC11304831 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature