Screening significance of systemic immune-inflammation index (SII) and systemic inflammation response index (SIRI) in coronary heart disease of symptomatic youth.

ABSTRACT:

Background

The incidence of coronary heart disease (CHD) in youth is rapidly increasing but difficultly recognized in the early stage.

Methods and results

In this retrospective study, 194 CHD patients under the age of 45 who previously experienced chest pain symptoms and 170 non-CHD patients were included and demographic data were collected. Systemic inflammation index (SII) and systemic inflammation response index (SIRI) were increased in young CHD patients (p < 001). Spearman's correlation analysis showed that both SII and SIRI were negatively correlated with HDL and positively correlated with hypertension, Gensini score, and hsTnI. Logistic regression analysis indicated that SII and SIRI were independently associated with the presence of CHD in youth with chest pain sympt

SUBMITTER: Wang C 

PROVIDER: S-EPMC11304894 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature