History of childhood maltreatment associated with hospitalization or death due to COVID-19: a cohort study.

ABSTRACT:

Background

Childhood maltreatment (CM) has been indicated in adverse health outcomes across the lifespan, including severe infection-related outcomes. Yet, data are scarce on the potential role of CM in severe COVID-19-related outcomes as well as on mechanisms underlying this association.

Methods

We included 151,427 individuals in the UK Biobank who responded to questions on the history of CM in 2016 and 2017 and were alive on January 31, 2020. Binomial logistic regression models were performed to estimate the association between a history of CM and severe COVID-19 outcomes (i.e. hospitalization or death due to COVID-19), as well as COVID-19 diagnosis and vaccination as secondary outcomes. We then explored the potential mediating roles of socio-economic status, lifestyle and

SUBMITTER: Wang Y 

PROVIDER: S-EPMC11304908 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature