Optimizing UVA and UVC synergy for effective control of harmful cyanobacterial blooms.

ABSTRACT: Harmful cyanobacterial blooms (HCBs) pose a global ecological threat. Ultraviolet C (UVC) irradiation at 254 nm is a promising method for controlling cyanobacterial proliferation, but the growth suppression is temporary. Resuscitation remains a challenge with UVC application, necessitating alternative strategies for lethal effects. Here, we show synergistic inhibition of Microcystis aeruginosa using ultraviolet A (UVA) pre-irradiation before UVC. We find that low-dosage UVA pre-irradiation (1.5 J cm^-2) combined with UVC (0.085 J cm^-2) reduces 85% more cell densities compared to UVC alone (0.085 J cm^-2) and triggers mazEF-mediated regulated cell death (RCD), which led to cell lysis, while high-dosage UVA pre-irradiations (7.5 and 14.7 J cm

SUBMITTER: Zhu Y 

PROVIDER: S-EPMC11305005 | biostudies-literature | 2024 Nov

REPOSITORIES: biostudies-literature