Ambient Air Pollution Exposures and Child Executive Function: A US Multicohort Study.

ABSTRACT:

Background

Executive function, which develops rapidly in childhood, enables problem-solving, focused attention, and planning. Animal models describe executive function decrements associated with ambient air pollution exposure, but epidemiologic studies are limited.

Methods

We examined associations between early childhood air pollution exposure and school-aged executive function in 1235 children from three US pregnancy cohorts in the ECHO-PATHWAYS Consortium. We derived point-based residential exposures to ambient particulate matter ≤2.5 µm in aerodynamic diameter (PM 2.5 ), nitrogen dioxide (NO 2 ), and ozone (O 3 ) at ages 0-4 years from spatiotemporal models with a 2-week resolution. We assessed executive function across three domains, cognitive flexibility, working memory

SUBMITTER: Ni Y 

PROVIDER: S-EPMC11305919 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature