Effect of Hormone Replacement Therapy on Chronic Rhinosinusitis Management.

ABSTRACT:

Objectives

To investigate whether hormone replacement therapy (HRT) impacts health care resource utilization in the management of chronic rhinosinusitis (CRS) in older women.

Methods

Using the TriNetX US health record database, women 55 years or older with a diagnosis of CRS were included and followed for 3 years. The cohort was stratified into two groups: women who received HRT at the beginning of the study were compared to women who did not receive HRT. The groups were matched by age, race, ethnicity, history of asthma, and history of nasal polyps. Outcomes included whether the patient underwent endoscopic sinus surgery (ESS) and frequency of antibiotic use. Measures of association, Kaplan-Meier analysis, and cohort descriptive statistics were calculated.

Results

Of

SUBMITTER: Herrera K 

PROVIDER: S-EPMC11305951 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature