Relationships between lung function, allergy, and wheezing in urban children.

ABSTRACT:

Background

Allergic sensitization and low lung function in early childhood are risk factors for subsequent wheezing and asthma. However, it is unclear how allergic sensitization affects lung function over time.

Objective

We sought to test whether allergy influences lung function and whether these factors synergistically increase the risk of continued wheezing in childhood.

Methods

We analyzed longitudinal measurements of lung function (spirometry and impulse oscillometry) and allergic sensitization (aeroallergen skin tests and serum allergen-specific IgE) throughout early childhood in the Urban Environmental and Childhood Asthma study, which included high-risk urban children living in disadvantaged neighborhoods. Intraclass correlation coefficients were calculated to

SUBMITTER: Konno-Yamamoto A 

PROVIDER: S-EPMC11305952 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature