Toxicological evaluation of copper oxide nanoparticles following their intraperitoneal injection to Wistar rats.

ABSTRACT:

Background

Copper oxide (Cu₂O) nanoparticles (CO NPs) are in extensive use during our everyday life as antimicrobial agent, lubricant, in manufacturing electrodes of lithium ion batteries as well as for photo catalytic degradation of organic pollutants. Due to extensive and diverse use Cu₂O NPs, they are likely to accumulate in the environment and to affect the live forms. Present investigation was aimed to report the biocompatibility of CO NPs in Wistar rats in sex specific manner. CO NPs, having average diameter of 14.06 nm, were synthesized by co-precipitation method and scanning electron microscopy and X ray diffraction were used for their characterization.

Methods

For 14 consecutive days, Wistar rats (6 weeks old) of both sexes were intraperitoneal

SUBMITTER: Shareef N 

PROVIDER: S-EPMC11306316 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature