Molecular folding governs switchable singlet oxygen photoproduction in porphyrin-decorated bistable rotaxanes.

ABSTRACT: Rotaxanes are mechanically interlocked molecules where a ring (macrocycle) is threaded onto a linear molecule (thread). The position of the macrocycle on different stations on the thread can be controlled in response to external stimuli, making rotaxanes applicable as molecular switches. Here we show that bistable rotaxanes based on the combination of a Zn(II) tetraphenylporphyrin photosensitizer, attached to the macrocycle, and a black-hole-quencher, attached to the thread, are capable of singlet oxygen production which can be switched on/off by the addition of base/acid. However, we found that only a sufficiently long linker between both stations on the thread enabled switchability, and that the direction of switching was inversed with regard to the original design. This unexpected behav

SUBMITTER: Riebe J 

PROVIDER: S-EPMC11306352 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature