Longitudinal change of energy expenditure, body composition and dietary habits in Progressive Supranuclear Palsy patients.

ABSTRACT:

Introduction

Alterations in metabolic status, body composition, and food intake are present in all neurodegenerative diseases. Aim of this study was to detect the progression of these changes in Progressive Supranuclear Palsy (PSP).

Methods

We conducted a longitudinal study of 15 patients with PSP. The assessments were performed at baseline (T0) and after 7(IQR = 5) months of follow-up (T1). We collected anthropometric measures including body weight, height, body mass index and waist circumference, metabolic parameters through indirect calorimeters, body composition using bioimpedance analysis, and dietary habits with a validated questionnaire. PSP-rating scale (PSP-rs) was used to evaluate disease severity and dysphagia.

Results

The majority of patients (66.66%) pres

SUBMITTER: Tepedino MF 

PROVIDER: S-EPMC11306440 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature