Association in Clinical Practice Between Gluten Intake and Gluten Immunogenic Peptides in Celiac Children.

ABSTRACT:

Background and aims

The dietary compliance and its assessment in celiac disease (CD) patients on a strict gluten-free diet (GFD) remain a challenge. Two relatively new, validated methods have been proposed to detect occasional gluten ingestion: standardized dietary questionnaire and determination of urinary gluten immunogenic peptides (GIPs). Our aim was to prospectively assess dietary compliance via these methods and compare their results with those of tissue transglutaminase antibodies (tTGA).

Methods

This was a prospective single-center study. Consecutive CD patients (aged 1-18 years) on a GFD scheduled for regular consultation between March and August 2019 were invited. In addition to standard care, a completed dietary questionnaire and urine sample for GIP were collecte

SUBMITTER: Meijer CR 

PROVIDER: S-EPMC11307387 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature