ISR vs De Novo Lesion Treatment During OCT-Guided PCI: Insights From the LightLab Initiative.

ABSTRACT:

Background

Long-term outcomes after percutaneous coronary intervention (PCI) for in-stent restenosis (ISR) are poor, yet limited granular procedural data exist evaluating lesion assessment, vessel treatment, and acute procedural outcomes.

Methods

The LightLab Initiative was a multicenter, prospective, observational study with contemporaneous procedural data collection during PCI procedures. Data were collected during PCIs performed by 48 interventional cardiologists at 17 US hospitals (2019-2021). Optical coherence tomography (OCT) was performed pre-PCI for lesion assessment and post-PCI for stent optimization, and results were compared between ISR and de novo lesion PCI.

Results

In total, 2592 OCT-guided PCIs involving 2944 lesions were included, of which 458 procedu

SUBMITTER: Bergmark BA 

PROVIDER: S-EPMC11307692 | biostudies-literature | 2023 Nov-Dec

REPOSITORIES: biostudies-literature