Optical Coherence Tomography Measures Predicting Fractional Flow Reserve: The OMEF Study.

ABSTRACT:

Background

Optical coherence tomography (OCT) allows to carefully characterize coronary plaque morphology and lumen dimensions. We sought to evaluate the value of OCT in predicting fractional flow reserve (FFR).

Methods

We performed a multicenter, international, pooled analysis of individual patient-level data from published studies assessing FFR and OCT on the same vessel. Data from stable or unstable patients who underwent both FFR and OCT of the same coronary artery were collected through a dedicated database. Predefined OCT parameters were minimum lumen area (MLA), percentage area stenosis (%AS), and presence of thrombus or plaque rupture. Primary end point was FFR ≤0.80. Secondary outcome was the incidence of major adverse cardiac events in patients not undergoing revas

SUBMITTER: Vergallo R 

PROVIDER: S-EPMC11307753 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature