Accounting for Liver Transplant in Acute Liver Failure Research.

ABSTRACT:

Background and aims

Acute liver failure (ALF) is a rare but serious disease with challenging clinical decisions, including the possibility of liver transplantation. Although there is interest in predicting who will need a transplant, that outcome is difficult to define as the decision to transplant includes many extraneous factors. The majority of research in this setting focuses on identifying factors that can provide guidance on a patient's likelihood of survival without a liver transplant. The question that arises is whether death and transplant should be combined as a poor outcome or should alternative approaches be used to account for transplant in this setting. Furthermore, does the approach to incorporating transplant information impact the accuracy of predicting survival. W

SUBMITTER: Livingston SI 

PROVIDER: S-EPMC11308213 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature