The Prognostic Significance of the Platelet Count in Alcoholic Hepatitis.

ABSTRACT:

Background and aims

Thrombocytopenia is present in up to 76% of patients with chronic liver disease, and lower platelet counts (PCs) are associated with greater severity of portal hypertension. In this study, we assess the relationship of PC in patients with a clinical diagnosis of severe alcoholic hepatitis (SAH) with clinical severity and response to corticosteroid (CS) therapy.

Methods

Clinical characteristics, treatment, and hospital outcomes for patients admitted with SAH were analyzed from an electronic health record system. Patients were categorized based on admission PC (k/uL) into 5 categories: <50, 50-99, 100-149, 150-199, and ≥200. Frequency of complications (acute kidney injury, ascites, and hepatic encephalopathy), length of stay, and admission to an intensive c

SUBMITTER: Birnbaum JA 

PROVIDER: S-EPMC11308416 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature