Diagnostic Performance of Intracoronary Optical Coherence Tomography-Modulated Quantitative Flow Ratio for Assessing Coronary Stenosis.

ABSTRACT:

Background

A novel method for fast computation of Murray law-based quantitative flow ratio (μQFR) from coregistered angiography and optical coherence tomography (OCT) was recently developed. This study aimed to evaluate the diagnostic performance of this OCT-modulated μQFR (OCT-μFR).

Methods

Patients who underwent coronary angiography, OCT, and fractional flow reserve (FFR) were retrospectively enrolled. μQFR was computed from a single angiographic projection. Subsequently, OCT image pullback was coregistered with the angiogram, and OCT-μFR was calculated based on the coregistered data. The same cut-off value of 0.80 was used for OCT-μFR, μQFR, and FFR to define ischemia.

Results

A paired comparison of OCT-μFR and μQFR was performed in 269 vessels from 218 patients. T

SUBMITTER: Xu T 

PROVIDER: S-EPMC11308763 | biostudies-literature | 2023 Sep-Oct

REPOSITORIES: biostudies-literature